Peptulator

Tirzepatide dosage calculator

In a 30 mg vial with 3 mL of water (10 mg/mL), 2.5 mg of Tirzepatide is 25 units on a U-100 insulin syringe. The whole 2.5 to 15 mg ladder, converted into the mark on your syringe. Works for 10, 20, 30 and 60 mg vials.

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Dose to units at the usual vial and water

DoseU-100 unitsDrawDoses per vialVial lasts
2.5 mg25 units0.25 mL1284 days
5 mg50 units0.5 mL642 days
7.5 mg75 units0.75 mL428 days
10 mg100 units1 mL321 days
12.5 mg125 units1.25 mL214 days
15 mg150 units1.5 mL214 days

30 mg vial in 3 mL of bacteriostatic water (10 mg/mL), U-100 insulin syringe, once weekly.

About Tirzepatide

Tirzepatide is a dual GIP and GLP-1 receptor agonist. The licensed titration ladder steps every four weeks: 2.5, 5, 7.5, 10, 12.5 and 15 mg once weekly, with 2.5 mg treated as a starting dose rather than a maintenance one.

Note that the licensed product is a pre-filled pen at a fixed concentration. Reconstituting a vial yourself means you set the concentration, so the unit numbers below will not match anything printed on a pen.

Switching from a pen or a Lilly vial to a vial you mixed

Every US Mounjaro and Zepbound single-dose pen, and every Zepbound single-dose vial, holds one dose in the same 0.5 mL. Lilly changes the strength, not the volume: 2.5 mg/0.5 mL is 5 mg/mL, and 15 mg/0.5 mL is 30 mg/mL. So on the licensed product you always injected 0.5 mL, which is 50 units on a U-100 insulin syringe, whatever your dose was. A vial you reconstitute yourself is the other way round: one concentration for every dose, so the volume changes with the dose. Your old 0.5 mL tells you nothing about the new draw.

Weekly doseLicensed pen or vial30 mg vial + 3 mL (10 mg/mL)60 mg vial + 3 mL (20 mg/mL)10 mg vial + 2 mL (5 mg/mL)
2.5 mg5 mg/mL, 0.5 mL (50 units)25 units12.5 units50 units
5 mg10 mg/mL, 0.5 mL (50 units)50 units25 units100 units
7.5 mg15 mg/mL, 0.5 mL (50 units)75 units37.5 units150 units (over one 1 mL syringe)
10 mg20 mg/mL, 0.5 mL (50 units)100 units50 units200 units (over one 1 mL syringe)
12.5 mg25 mg/mL, 0.5 mL (50 units)125 units (over one 1 mL syringe)62.5 unitsmore than the vial holds
15 mg30 mg/mL, 0.5 mL (50 units)150 units (over one 1 mL syringe)75 unitsmore than the vial holds

Units on a U-100 insulin syringe (100 units = 1 mL). The licensed column is from Lilly's Zepbound vial instructions; pens use the same 0.5 mL per dose.

Three worked examples

5 mg, from a 30 mg vial with 3 mL. 30 ÷ 3 is 10 mg/mL, the same strength as the licensed 5 mg dose (5 mg in 0.5 mL). 5 mg ÷ 10 mg/mL is 0.5 mL, so the mark is 50 units, the one case where the familiar 50 is right.

7.5 mg, same 30 mg vial. Still 10 mg/mL, so 7.5 mg is 0.75 mL: 75 units, not 50. From a 60 mg vial with 3 mL (20 mg/mL) it is 37.5 units.

15 mg. At 10 mg/mL that is 1.5 mL, 150 units, more than a 1 mL syringe holds. A 60 mg vial with 3 mL puts it at 75 units, and 12.5 mg at 62.5 units, so the top of the ladder fits one draw.

Mistakes that come from the pen

Sources

The same 30 mg vial at other water volumes

If the draw is awkward to read, change the water, not the dose. The dose stays the same; only the mark moves.

VialBAC waterConcentrationDrawU-100 unitsDoses/vial
30 mg2 mL15 mg/mL0.167 mL16.7 units12
30 mg3 mL10 mg/mL0.25 mL25 units12
30 mg5 mL6 mg/mL0.417 mL41.7 units12
60 mg2 mL30 mg/mL0.083 mL8.3 units24
60 mg3 mL20 mg/mL0.125 mL12.5 units24
60 mg5 mL12 mg/mL0.208 mL20.8 units24

All rows above assume a 2.5 mg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.

How long it lasts in the body

The half-life of Tirzepatide is about 5 days. That is the time for the amount in your blood to halve, so after one half-life you are at 50 percent of the peak, after two you are at 25 percent, and after four you are at roughly 6 percent. This is why a weekly compound still has meaningful levels present when the next dose lands, and why levels build over the first several weeks before they settle.

100%75%50%25%0%one half-life0 d5 d10 d15 d20 d

Common questions

How many units is 2.5 mg of Tirzepatide?
It depends entirely on how much water you added. In a 30 mg vial reconstituted with 3 mL, the concentration is 10 mg/mL, so 2.5 mg is 0.25 mL, which is 25 units on a U-100 insulin syringe. In the same vial with 1.5 mL of water it is 12.5 units, and with 4.5 mL it is 37.5 units.
How much bacteriostatic water for a 30 mg Tirzepatide vial?
3 mL is the usual choice. It gives 10 mg/mL, which puts the commonly reported range of 1 mg to 15 mg between roughly 10 and 150 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
How many doses are in a 30 mg vial?
Divide 30 by your dose. At 2.5 mg that is 12 doses, which at once weekly is 84 days.
Is compounded tirzepatide the same as the licensed product?
No. Concentration, excipients and quality control differ. Anything you reconstitute yourself is at a concentration you chose, so unit counts from a pen do not transfer.
IndependentThis site does not sell peptides and is not owned by a vendor.
The maths is openThe formula is on every page and in the methodology. The code is one file with an automated test suite, run before each deploy.
How it is fundedNo ads and no vendor links here. It is published by the team behind Peptide Bureau, which earns from affiliate links on its own site, and VialHaus, the same team's vial storage shop, which the storage notes link to.
ReviewedDose ranges and half-lives checked 3 September 2026.

Buying Tirzepatide?

Peptulator does not list, rank or link vendors. Whoever the supplier is, use the strength printed on your own vial and check the batch certificate of analysis before you rely on any number here.

Common conversions

The same three-step maths, pre-filled for the doses people ask about most. Units on a U-100 insulin syringe, where 100 units is 1 mL.

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Before you use these numbers This is a unit-conversion tool. It turns a vial strength and a water volume into a concentration, a draw volume and a syringe mark. It does not tell you what to take, whether to take it, or whether a compound is safe for you. Most compounds listed are sold for laboratory research and are not approved for human use. Nothing here is medical advice. Dosing decisions belong with a licensed clinician who knows your history. Always check the strength printed on your own vial rather than trusting a preset.