MOTS-c dosage calculator
In a 10 mg vial with 2 mL of water (5 mg/mL), 5 mg of MOTS-c is 100 units on a U-100 insulin syringe. MOTS-c is dosed in whole milligrams a few times a week, so the draw is large.
25 printable pages: dosing cards for the twelve most-used compounds at three water volumes, titration planners, a vial log, and five pages on what to do when it has already gone wrong.
Dose to units at the usual vial and water
| Dose | U-100 units | Draw | Doses per vial | Vial lasts |
|---|---|---|---|---|
| 2.5 mg | 50 units | 0.5 mL | 4 | 9 days |
| 5 mg | 100 units | 1 mL | 2 | 5 days |
| 7.5 mg | 150 units | 1.5 mL | 1 | 2 days |
| 10 mg | 200 units | 2 mL | 1 | 2 days |
10 mg vial in 2 mL of bacteriostatic water (5 mg/mL), U-100 insulin syringe, three times a week.
About MOTS-c
MOTS-c is a 16 amino acid peptide encoded in mitochondrial DNA, studied for its effects on metabolism and exercise capacity. It is not an approved medicine and is sold for research use.
Reported protocols are unusual for a peptide: whole milligram doses, 5 to 10 mg, two or three times a week, sometimes as a short daily course. A 10 mg vial with 2 mL of water is 5 mg/mL, so 5 mg is 1 mL, a full U-100 syringe. If you are dosing 10 mg from a 10 mg vial, that is the entire vial, and how much water you add only changes how many injections it takes to get it in. The MOTS-c dosage chart page lays all of this out at three water volumes.
The same 10 mg vial at other water volumes
If the draw is awkward to read, change the water, not the dose. The dose stays the same; only the mark moves.
| Vial | BAC water | Concentration | Draw | U-100 units | Doses/vial |
|---|---|---|---|---|---|
| 10 mg | 1 mL | 10 mg/mL | 0.5 mL | 50 units | 2 |
| 10 mg | 2 mL | 5 mg/mL | 1 mL | 100 units | 2 |
| 10 mg | 3 mL | 3.33 mg/mL | 1.5 mL | 150 units | 2 |
| 40 mg | 1 mL | 40 mg/mL | 0.125 mL | 12.5 units | 8 |
| 40 mg | 2 mL | 20 mg/mL | 0.25 mL | 25 units | 8 |
| 40 mg | 3 mL | 13.33 mg/mL | 0.375 mL | 37.5 units | 8 |
All rows above assume a 5 mg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.
How long it lasts in the body
Not well characterised in humans. A decay curve is only drawn where a human half-life is documented, so there is none here. Treat any precise figure for MOTS-c elsewhere with caution.
Common questions
- How many units is 5 mg of MOTS-c?
- It depends entirely on how much water you added. In a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so 5 mg is 1 mL, which is 100 units on a U-100 insulin syringe. In the same vial with 1 mL of water it is 50 units, and with 3 mL it is 150 units.
- How much bacteriostatic water for a 10 mg MOTS-c vial?
- 2 mL is the usual choice. It gives 5 mg/mL, which puts the commonly reported range of 2.5 mg to 10 mg between roughly 50 and 200 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
- How many doses are in a 10 mg vial?
- Divide 10 by your dose. At 5 mg that is 2 doses, which at three times a week is 5 days.
- How many units is 5 mg of MOTS-c?
- In a 10 mg vial with 2 mL of water, 100 units, a full 1 mL syringe. In a 10 mg vial with 1 mL of water, 50 units.
Buying MOTS-c?
Peptulator does not list, rank or link vendors. Whoever the supplier is, use the strength printed on your own vial and check the batch certificate of analysis before you rely on any number here.
Common conversions
The same three-step maths, pre-filled for the doses people ask about most. Units on a U-100 insulin syringe, where 100 units is 1 mL.
- mg to units calculator Any dose at any concentration, both directions, with the full reference tables
- Units to mg calculator What the units you drew are in milligrams
- 1 mg to units The most-asked conversion, at every common setup
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- MOTS-c calculator (this page)
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