Peptulator

MOTS-c dosage calculator

In a 10 mg vial with 2 mL of water (5 mg/mL), 5 mg of MOTS-c is 100 units on a U-100 insulin syringe. MOTS-c is dosed in whole milligrams a few times a week, so the draw is large.

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Dose to units at the usual vial and water

DoseU-100 unitsDrawDoses per vialVial lasts
2.5 mg50 units0.5 mL49 days
5 mg100 units1 mL25 days
7.5 mg150 units1.5 mL12 days
10 mg200 units2 mL12 days

10 mg vial in 2 mL of bacteriostatic water (5 mg/mL), U-100 insulin syringe, three times a week.

About MOTS-c

MOTS-c is a 16 amino acid peptide encoded in mitochondrial DNA, studied for its effects on metabolism and exercise capacity. It is not an approved medicine and is sold for research use.

Reported protocols are unusual for a peptide: whole milligram doses, 5 to 10 mg, two or three times a week, sometimes as a short daily course. A 10 mg vial with 2 mL of water is 5 mg/mL, so 5 mg is 1 mL, a full U-100 syringe. If you are dosing 10 mg from a 10 mg vial, that is the entire vial, and how much water you add only changes how many injections it takes to get it in. The MOTS-c dosage chart page lays all of this out at three water volumes.

The same 10 mg vial at other water volumes

If the draw is awkward to read, change the water, not the dose. The dose stays the same; only the mark moves.

VialBAC waterConcentrationDrawU-100 unitsDoses/vial
10 mg1 mL10 mg/mL0.5 mL50 units2
10 mg2 mL5 mg/mL1 mL100 units2
10 mg3 mL3.33 mg/mL1.5 mL150 units2
40 mg1 mL40 mg/mL0.125 mL12.5 units8
40 mg2 mL20 mg/mL0.25 mL25 units8
40 mg3 mL13.33 mg/mL0.375 mL37.5 units8

All rows above assume a 5 mg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.

How long it lasts in the body

Not well characterised in humans. A decay curve is only drawn where a human half-life is documented, so there is none here. Treat any precise figure for MOTS-c elsewhere with caution.

Common questions

How many units is 5 mg of MOTS-c?
It depends entirely on how much water you added. In a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so 5 mg is 1 mL, which is 100 units on a U-100 insulin syringe. In the same vial with 1 mL of water it is 50 units, and with 3 mL it is 150 units.
How much bacteriostatic water for a 10 mg MOTS-c vial?
2 mL is the usual choice. It gives 5 mg/mL, which puts the commonly reported range of 2.5 mg to 10 mg between roughly 50 and 200 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
How many doses are in a 10 mg vial?
Divide 10 by your dose. At 5 mg that is 2 doses, which at three times a week is 5 days.
How many units is 5 mg of MOTS-c?
In a 10 mg vial with 2 mL of water, 100 units, a full 1 mL syringe. In a 10 mg vial with 1 mL of water, 50 units.
IndependentThis site does not sell peptides and is not owned by a vendor.
The maths is openThe formula is on every page and in the methodology. The code is one file with an automated test suite, run before each deploy.
How it is fundedNo ads and no vendor links here. It is published by the team behind Peptide Bureau, which earns from affiliate links on its own site, and VialHaus, the same team's vial storage shop, which the storage notes link to.
ReviewedDose ranges and half-lives checked 3 September 2026.

Buying MOTS-c?

Peptulator does not list, rank or link vendors. Whoever the supplier is, use the strength printed on your own vial and check the batch certificate of analysis before you rely on any number here.

Common conversions

The same three-step maths, pre-filled for the doses people ask about most. Units on a U-100 insulin syringe, where 100 units is 1 mL.

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Before you use these numbers This is a unit-conversion tool. It turns a vial strength and a water volume into a concentration, a draw volume and a syringe mark. It does not tell you what to take, whether to take it, or whether a compound is safe for you. Most compounds listed are sold for laboratory research and are not approved for human use. Nothing here is medical advice. Dosing decisions belong with a licensed clinician who knows your history. Always check the strength printed on your own vial rather than trusting a preset.