MOTS-c dosage calculator
MOTS-c is dosed in whole milligrams a few times a week, so the draw is large. Enter the vial, the water and your dose and see where it lands on the syringe.
Dose to units, at the standard setup
| Dose | Draw | U-100 units | Doses per vial | Vial lasts |
|---|---|---|---|---|
| 2.5 mg | 0.5 mL | 50 units | 4 | 9 days |
| 5 mg | 1 mL | 100 units | 2 | 5 days |
| 7.5 mg | 1.5 mL | 150 units | 1 | 2 days |
| 10 mg | 2 mL | 200 units | 1 | 2 days |
Based on a 10 mg vial reconstituted with 2 mL of bacteriostatic water, which is 5 mg/mL, drawn on a standard U-100 insulin syringe, three times a week.
About the numbers above
MOTS-c is a 16 amino acid peptide encoded in mitochondrial DNA, studied for its effects on metabolism and exercise capacity. It is not an approved medicine and is sold for research use.
Reported protocols are unusual for a peptide: whole milligram doses, 5 to 10 mg, two or three times a week, sometimes as a short daily course. A 10 mg vial with 2 mL of water is 5 mg/mL, so 5 mg is 1 mL, a full U-100 syringe. If you are dosing 10 mg from a 10 mg vial, that is the entire vial, and how much water you add only changes how many injections it takes to get it in. The MOTS-c dosage chart page lays all of this out at three water volumes.
A 10 mg vial at different water volumes
If the draw feels awkward to read, change the water rather than the dose. The dose stays the same; only the mark moves.
| Vial | BAC water | Concentration | Draw | U-100 units | Doses/vial |
|---|---|---|---|---|---|
| 10 mg | 1 mL | 10 mg/mL | 0.5 mL | 50 units | 2 |
| 10 mg | 2 mL | 5 mg/mL | 1 mL | 100 units | 2 |
| 10 mg | 3 mL | 3.33 mg/mL | 1.5 mL | 150 units | 2 |
| 40 mg | 1 mL | 40 mg/mL | 0.125 mL | 12.5 units | 8 |
| 40 mg | 2 mL | 20 mg/mL | 0.25 mL | 25 units | 8 |
| 40 mg | 3 mL | 13.33 mg/mL | 0.375 mL | 37.5 units | 8 |
All rows above assume a 5 mg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.
How long it stays in you
Not well characterised in humans. This site only draws a decay curve where a half-life is actually documented in humans, so there is none here. Treat any precise figure you see elsewhere for MOTS-c with suspicion.
Common questions
- How many units is 5 mg of MOTS-c?
- It depends entirely on how much water you added. In a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so 5 mg is 1 mL, which is 100 units on a U-100 insulin syringe. In the same vial with 1 mL of water it is 50 units, and with 3 mL it is 150 units.
- How much bacteriostatic water for a 10 mg MOTS-c vial?
- 2 mL is the usual choice. It gives 5 mg/mL, which puts the commonly reported range of 2.5 mg to 10 mg between roughly 50 and 200 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
- How many doses are in a 10 mg vial?
- Divide 10 by your dose. At 5 mg that is 2 doses, which at three times a week is 5 days.
- How many units is 5 mg of MOTS-c?
- In a 10 mg vial with 2 mL of water, 100 units, a full 1 mL syringe. In a 10 mg vial with 1 mL of water, 50 units.
Every calculator and chart on this site
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Dosage charts and schedules
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Tools
- Peptide calculator The general tool, any compound
- Reconstitution calculator How much water to add, and why it matters
- mg to units calculator Both directions, any concentration
- Bacteriostatic water calculator Pick a volume that lands where you can read it
- How to read an insulin syringe U-100 vs U-40, and the 2.5x error
- The Protocol Pack Free 25-page printable reference
- Where to buy Vendor notes and what to check first
- 1 mg to units on an insulin syringe The conversion table for every common concentration