TB-500 dosage calculator
TB-500 is dosed in whole milligrams, usually twice a week, with a higher loading phase first. Enter your vial, water and dose to get the mark.
Dose to units, at the standard setup
| Dose | Draw | U-100 units | Doses per vial | Vial lasts |
|---|---|---|---|---|
| 1 mg | 0.4 mL | 40 units | 5 | 18 days |
| 2 mg | 0.8 mL | 80 units | 2 | 7 days |
| 2.5 mg | 1 mL | 100 units | 2 | 7 days |
| 5 mg | 2 mL | 200 units | 1 | 4 days |
| 7.5 mg | 3 mL | 300 units | needs a bigger vial | - |
| 10 mg | 4 mL | 400 units | needs a bigger vial | - |
Based on a 5 mg vial reconstituted with 2 mL of bacteriostatic water, which is 2.5 mg/mL, drawn on a standard U-100 insulin syringe, twice weekly.
About the numbers above
TB-500 is a synthetic fragment of thymosin beta-4, a protein involved in cell migration and tissue repair. It is not an approved medicine and is sold for research use.
Reported protocols usually have two phases: a loading phase of roughly 4 to 10 mg per week split into two injections for four to six weeks, then a lower maintenance dose. A 5 mg vial with 2 mL of water is 2.5 mg/mL, so 2 mg is 0.8 mL, or 80 units. Doses of 5 mg from a 5 mg vial are the whole vial. Because the draws are large, use 1 mL syringes here, and if the calculator warns the draw exceeds the syringe, use less water or split the injection.
A 5 mg vial at different water volumes
If the draw feels awkward to read, change the water rather than the dose. The dose stays the same; only the mark moves.
| Vial | BAC water | Concentration | Draw | U-100 units | Doses/vial |
|---|---|---|---|---|---|
| 5 mg | 1 mL | 5 mg/mL | 0.4 mL | 40 units | 2 |
| 5 mg | 2 mL | 2.5 mg/mL | 0.8 mL | 80 units | 2 |
| 5 mg | 3 mL | 1.67 mg/mL | 1.2 mL | 120 units | 2 |
| 10 mg | 1 mL | 10 mg/mL | 0.2 mL | 20 units | 5 |
| 10 mg | 2 mL | 5 mg/mL | 0.4 mL | 40 units | 5 |
| 10 mg | 3 mL | 3.33 mg/mL | 0.6 mL | 60 units | 5 |
All rows above assume a 2 mg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.
How long it stays in you
Not well characterised in humans. This site only draws a decay curve where a half-life is actually documented in humans, so there is none here. Treat any precise figure you see elsewhere for TB-500 with suspicion.
Common questions
- How many units is 2 mg of TB-500?
- It depends entirely on how much water you added. In a 5 mg vial reconstituted with 2 mL, the concentration is 2.5 mg/mL, so 2 mg is 0.8 mL, which is 80 units on a U-100 insulin syringe. In the same vial with 1 mL of water it is 40 units, and with 3 mL it is 120 units.
- How much bacteriostatic water for a 5 mg TB-500 vial?
- 2 mL is the usual choice. It gives 2.5 mg/mL, which puts the commonly reported range of 0.5 mg to 10 mg between roughly 20 and 400 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
- How many doses are in a 5 mg vial?
- Divide 5 by your dose. At 2 mg that is 2 doses, which at twice weekly is 7 days.
- How many units is 2.5 mg of TB-500?
- In a 5 mg vial with 2 mL of water, 100 units, a full syringe. With 1 mL of water, 50 units.
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