Peptide Calculator

Melanotan II dosage calculator

Melanotan II is dosed in micrograms from a 10 mg vial. Enter your water and dose to get the syringe mark, and see how the small starting doses land on the barrel.

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ReviewedDose ranges and half-life figures last checked 3 September 2026.

Dose to units, at the standard setup

DoseDrawU-100 unitsDoses per vialVial lasts
100 mcg0.02 mL2 units100100 days
250 mcg0.05 mL5 units4040 days
500 mcg0.1 mL10 units2020 days
750 mcg0.15 mL15 units1313 days
1000 mcg0.2 mL20 units1010 days

Based on a 10 mg vial reconstituted with 2 mL of bacteriostatic water, which is 5 mg/mL, drawn on a standard U-100 insulin syringe, once daily.

About the numbers above

Melanotan II is a synthetic analogue of alpha-MSH that darkens skin by stimulating melanin. It is not approved anywhere, has been the subject of regulator warnings, and is sold for research. Nausea, flushing and new or darkening moles are the most reported effects.

Reports describe starting at 100 to 250 mcg to test tolerance, rising over days to 500 mcg or so, then dropping to occasional maintenance doses. A 10 mg vial with 2 mL of water is 5,000 mcg/mL, so 250 mcg is 0.05 mL, or 5 units. That is a small draw; 3 mL of water makes it 7.5 units. Melanotan I (afamelanotide) is a different, longer-acting compound with its own dosing.

A 10 mg vial at different water volumes

If the draw feels awkward to read, change the water rather than the dose. The dose stays the same; only the mark moves.

VialBAC waterConcentrationDrawU-100 unitsDoses/vial
10 mg1 mL10 mg/mL0.025 mL2.5 units40
10 mg2 mL5 mg/mL0.05 mL5 units40
10 mg3 mL3.33 mg/mL0.075 mL7.5 units40

All rows above assume a 250 mcg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.

How long it stays in you

Not well characterised in humans. This site only draws a decay curve where a half-life is actually documented in humans, so there is none here. Treat any precise figure you see elsewhere for Melanotan II with suspicion.

Common questions

How many units is 250 mcg of Melanotan II?
It depends entirely on how much water you added. In a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so 250 mcg is 0.05 mL, which is 5 units on a U-100 insulin syringe. In the same vial with 1 mL of water it is 2.5 units, and with 3 mL it is 7.5 units.
How much bacteriostatic water for a 10 mg Melanotan II vial?
2 mL is the usual choice. It gives 5 mg/mL, which puts the commonly reported range of 100 mcg to 1000 mcg between roughly 2 and 20 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
How many doses are in a 10 mg vial?
Divide 10 by your dose. At 250 mcg that is 40 doses, which at once daily is 40 days.
How many units is 250 mcg of Melanotan II?
In a 10 mg vial with 2 mL of water, 5 units on a U-100 syringe. With 1 mL of water it is 2.5 units, which is hard to read accurately.
Buying Melanotan II? The where to buy page lists the vendors this site uses and what to check before ordering, and Peptide Bureau keeps the ranked vendor scorecard.

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Read this before you use the numbers. This is a unit-conversion tool. It converts a vial strength and a volume of bacteriostatic water into a concentration, a draw volume and a mark on an insulin syringe. It does not tell you what to take, whether to take it, or whether a compound is safe for you. Most of the compounds listed here are sold for laboratory research use and are not approved for human use. Nothing on this site is medical advice. Dosing decisions belong with a licensed clinician who knows your history. Always confirm the strength printed on your own vial rather than trusting a preset.